David H K Chui Selected Research

Globins

1/2022	Pharmacologic induction of PGC-1α stimulates fetal haemoglobin gene expression.
5/2021	A Novel β0-Thalassemia Mutation, HBB: c.356_357delTT [Codon 118 (-TT)] in an Iraqi Kurd.
1/2019	Editing aberrant splice sites efficiently restores β-globin expression in β-thalassemia.
1/2018	Induced pluripotent stem cell-based mapping of β-globin expression throughout human erythropoietic development.
1/2018	A Mild Phenotype of Severe β+ Thalassemia in a 16-Month-Old Boy.
11/2017	A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells.
11/2016	A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia.
1/2016	Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia.
1/2016	Diverse hematological phenotypes of β-thalassemia carriers.
1/2016	Therapeutic fetal-globin inducers reduce transcriptional repression in hemoglobinopathy erythroid progenitors through distinct mechanisms.

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David H K Chui Research Topics

Disease

21	Thalassemia 05/2021 - 03/2002
21	Sickle Cell Anemia (Hemoglobin S Disease) 10/2019 - 11/2004
11	beta-Thalassemia (Cooley's Anemia) 01/2018 - 02/2002
9	Hemoglobinopathies 01/2022 - 01/2003
6	Anemia 11/2017 - 08/2010
4	Hydrops Fetalis (Fetal Edema) 01/2018 - 11/2003
4	alpha-Thalassemia 01/2018 - 01/2002
2	Hemolysis 06/2016 - 01/2014
2	Hemoglobin SC Disease (Disease, Hemoglobin SC) 01/2016 - 03/2011
2	Hemolytic Anemia 01/2014 - 11/2012
1	Infections 01/2022
1	Pain (Aches) 02/2019
1	Necrosis 11/2017
1	Acute Chest Syndrome 11/2017
1	Cholelithiasis 11/2017
1	Sickle Cell Trait 01/2016
1	Bone Marrow Failure Disorders 01/2015
1	Hypersplenism (Anemia, Splenic) 01/2015
1	Congenital Heart Defects (Congenital Heart Defect) 08/2013
1	Splenic Infarction 07/2013
1	Disease Progression 05/2006

Drug/Important Bio-Agent (IBA)

22	GlobinsIBA 01/2022 - 03/2002
19	Hemoglobins (Hemoglobin)IBA 02/2019 - 03/2002
15	Fetal Hemoglobin (Hemoglobin F)IBA 02/2019 - 01/2007
6	Codon (Codons)IBA 05/2021 - 02/2002
4	Sickle HemoglobinIBA 11/2017 - 07/2011
3	NucleotidesIBA 05/2021 - 03/2006
3	alpha-GlobinsIBA 01/2018 - 03/2005
3	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 01/2003
2	Messenger RNA (mRNA)IBA 01/2022 - 10/2019
2	EnzymesIBA 01/2016 - 01/2002
2	beta-Globins (beta Globin)IBA 02/2008 - 01/2007
2	hemoglobin Bart'sIBA 01/2005 - 11/2003
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	ZLN005IBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 02/2019
1	RibonucleoproteinsIBA 01/2019
1	hemoglobin AdanaIBA 01/2018
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2018
1	Long Noncoding RNAIBA 01/2018
1	hemoglobin Osu-ChristiansborgIBA 06/2016
1	Mi-2 Nucleosome Remodeling and Deacetylase ComplexIBA 01/2016
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2016
1	Prednisolone (Predate)FDA LinkGeneric 01/2015
1	Rituximab (Mabthera)FDA Link 01/2015
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2015
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2015
1	Hemoglobin A2IBA 11/2014
1	2,2-dimethylbutyric acidIBA 03/2014
1	hemoglobin YoungstownIBA 01/2014
1	Alanine (L-Alanine)FDA Link 01/2014
1	Amino Acids FDA Link 01/2014
1	Glutamic Acid (Glutamate)FDA Link 01/2014
1	hemoglobin M BostonIBA 10/2013
1	MethemoglobinIBA 08/2013
1	Oxygen (Dioxygen)IBA 08/2013
1	PolymersIBA 07/2011
1	MagnesiumIBA 03/2011
1	hemoglobin A2'IBA 01/2011
1	gamma-GlobinsIBA 08/2010
1	Hemoglobin EIBA 03/2010
1	Odorant Receptors (Odorant Receptor)IBA 03/2010
1	hemoglobin A(2)-RamallahIBA 01/2010
1	Hydroxyurea (Hydrea)FDA LinkGeneric 08/2007
1	Terminator Codon (Termination Codon)IBA 03/2006
1	hemoglobin HopeIBA 01/2004
1	GATIBA 01/2004
1	Nonsense Codon (Nonsense Mutation)IBA 08/2003
1	zeta-GlobinsIBA 01/2002
1	ImmunosorbentsIBA 01/2002

Therapy/Procedure

3	Therapeutics 11/2017 - 08/2010
1	Plasmapheresis 01/2015